منابع مشابه
Management of statin myopathy
With interest, we read the article by Sahebkar et al. about the proposal to treat patients with statin-induced myopathy (SIM) with curcumin in addition to the statin. We have the following comments and concerns. We do not agree with the statement in the introduction that pharmacotherapy for statin-myopathy is limited. The most effective treatment is discontinuation of the statin and adherence t...
متن کاملStatin-induced Myopathy
Heart disease (HD) is the number one killer in the United States.(1) In 2006, the direct and indirect costs associated with cardiovascular disease in the United States were estimated at 400 billion dollars.(2) Statin therapy for cholesterol reduction is a mainstay intervention for cardiovascular disease (CVD) as reflected in atorvastatin's status as the number one prescribed medication in the U...
متن کاملCLINICAL REVIEW Statin induced myopathy
Since their introduction for the treatment of hypercholesterolaemia in 1987, the use of statins has grown to over 100 million prescriptions per year. About 1.5-3% of statin users in randomised controlled trials and up to 10-13% of participants enrolled in prospective clinical studies develop myalgia. As a conservative estimate, at least 1.5 million people per year will experience amuscle relate...
متن کاملStatin-Induced Necrotizing Autoimmune Myopathy
A 76-year-old man with a history of two prior strokes complicated by residual mild cognitive impairment, atrial fibrillation, coronary artery disease, diabetes mellitus type 2, congestive heart failure, dyslipidemia, and stage 3 chronic kidney disease was admitted for failure to thrive and functional decline. Two months prior, he had been briefly hospitalized for fatigue and inability to walk. ...
متن کاملStatin-induced apoptosis and skeletal myopathy.
Over 100 million prescriptions were filled for statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) in 2004. Statins were originally developed to lower plasma cholesterol in patients with hypercholesterolemia and are the most effective drugs on the market in doing so. Because of the discovered pleiotropic effects of statins, the use has expanded to the treatment of many other co...
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ژورنال
عنوان ژورنال: Neurologie pro praxi
سال: 2017
ISSN: 1213-1814,1803-5280
DOI: 10.36290/neu.2017.058